Researchers from Anatomy@Edinburgh have developed an updated version of their NMJ-morph software platform for analyzing synaptic morphology. The automated macro – ‘aNMJ-morph’ – is freely available at Edinburgh DataShare and the supporting article has just been published in Royal Society Open Science. NMJ-morph allows different research groups to measure synapses and share data easily, whilst the new aNMJ-morph macro significantly increases the speed of data collection. These approaches have now been used in several major studies of the human neuromuscular junction (NMJ) in both health (Cell Reports) and disease (Journal of Clinical Investigation). Image Image: Minty G et al. 2020. aNMJ-morph: a simple macro for rapid analysis of neuromuscular junction morphology. Royal Society Open Science. 7: 200128. Related links Edinburgh DataShare 'aNMJ-morph' macro Royal Society Open Science - aNMJ-morph: a simple macro for rapid analysis of neuromuscular junction morphology Open Biology - NMJ-morph reveals principal components of synaptic morphology influencing structure–function relationships at the neuromuscular junction Cell Reports - Cellular and Molecular Anatomy of the Human Neuromuscular Junction Journal of Clinical Investigation - Neuromuscular junctions are stable in patients with cancer cachexia Publication date 28 Apr, 2020
