News

01/08/2025

We have been successful in our application to the BBSRC ALERT 2024 call to acquire a Nikon/CrestOptics X-Light V3/DeepSIM dual camera spinning disk confocal microscope with a DeepSIM super-resolution module. 

The CrestOptics Spinning disk unit, coupled with the Nikon Ti2 and dual Photometrics Kinetixs cameras allows for simultaneous 2 colour imaging of large (up to 25 mm), flat, fields of view. Interchangeable disk units will allow optimal fast live cell imaging (>1000fps) or imaging deep into tissue. The DeepSIM module can achieve resolutions down to 100 nm but can be used to give a 2-fold resolution improvement for nearly all objectives. With a spectral excitation range of 200 - 750 nm you will be able to broaden your choice of fluorophores into the near-IR.

The inclusion of Nikon JOBS and General Analysis 3 software modules will allow development of automatic imaging and analysis routines as well as event driven microscopy routines.

The microscope will initially be installed in the Hugh Robson Building, George Square in late 2025 and will relocate to QMRI in late 2026. The microscope will be available to internal and external academic researchers and interested commercial clients. Please contact Iain Porter for more information.

I would like to thank all the co-applicants from INCR and across CMVM for their help in putting the application together and I look forward to working on some interesting projects.

20/06/2025

In partnership with the Histology and Slide Scanning facility at the Institute for Regeneration and Repair we have brought slide scanning abilities to the IMPACT facility.

Please contact us for more information.

15/04/2025

We had to say goodbye to our trusty Nikon A1R confocal but we would like to welcome it's replacement in the form of the Nikon AXR-NSPARC.

With improved resonant scanner, more sensitive detectors and super-resolution NSPARC detector this system is approximately 5-fold faster than our previous system and can achieve resolutions down to 100nm. It is also a superb live-cell imaging confocal!

More information about this system can be found here.

15/12/2024

Our Zeiss Observer microscope has been upgraded with a new stage and AI sample finder.

Automatically find your samples on the slide, image at multiple magnifications and combine the images using Zen Connect.

Please see here for more information.

14/09/2024

Our Evident (Olympus) IX83 live cell imaging rig has been upgraded to a 4 colour Total Internal Reflection (TIRF) system. Contact IMPACT for more details.

31/07/2024

Our LSM800-Airyscan has been upgraded to Airyscan 2 with 2Y and 4Y scanning.

We have also had a software upgrade to include joint deconvolution (jDCV), advanced tile acquisition and Zen Connect.

See the Zeiss website here for more information.